The pet peeve issue I have with RPC/HTTP APIs is that people keep reinventing HTTP on top of it, only badly (at which point they may as well use RPC/TCP). That's why I like REST/HTTP, because I can "reuse things" when the problem model fits well within that tool (and it very often does). If REST/HTTP becomes a constraint instead of an asset, then maybe one should not use either REST or HTTP, and I'm fine with it because that was not the tool for the job.
This is a tool, not a religion.
Sometimes I have questions on which HTTP status code to use, but most of the time its pretty clear. And if you stick to the official codes most client side libraries will just work without any drama at all. As a bonus, all of the intermediate processes (proxies, firewalls, CDNs, etc.) will work as well without any finagling on your part. :)
In this case the client has sent an invalid request so the response should be 400 Bad Request or 422 Invalid Data, with details of the error in the response body.