Goodman juggles vastly different concepts of what a "meme" is without consistently distinguishing between them. He seems to dismiss memetics as an abstract model based on a lack of evidence for memes as physical entities, which, depending on how it's constructed, seems like either fringe absurdity (an idea particle) or a logical conclusion of materialism. And his question of whether an idea or its proponent "wins" is a poorly-defined non-sequitur.
The original question is bad, in my opinion. Assuming you acknowledge the existence of ideas, a better question would be "is meme theory a useful or accurate model of how ideas behave?"