I often try out new new web dev platforms and frameworks but tend to rewrite projects that get too serious or large in Django, or when I'm starting to miss too many features.
If I know that I am building something that others are going to work on, or if I know that the project will need to be maintained for a considerable amount of time, I tend to go with Django and a few familiar libraries (Celery, Django REST framework, django-extensions) right off the bat, as I feel comfortable that we won't run into issues where some important dependency becomes unmaintained or introduces backwards-incompatible changes. Much thanks to Django's predictable and well thought out releases.
Further, when I pick Django, I know that there is good support in monitoring and crash report systems such as Sentry, New Relic, and others. So that's one less thing to worry about.
The only area where I have started to use other solutions is frontend dev, as I find that the momentum in the Node community is so much higher in this area. I only wish that the Node community wasn't as fragmented and had a more long-term view on releases.