By contrast I think C++ and realtime audio programming is simple, but I've slowly picked it up over almost 20 years. I retreated back to desktop apps and firmware. I'll take another stab at learning web technologies, but not at a startup where I need to deliver asap and learn at the same time.
As much as developers hate sandboxes, the lack of one (except Mac OS until recently) is why I think desktop is failing. Users just don't feel safe installing random software like they do going to websites or installing mobile apps. Users have been conditioned to only install software from sources they trust, and they trust no one.
If I post a link to my new web project, most people will click on it. If I post a link to an .exe almost nobody will download it. I think that's the main issue killing the desktop. Big downloads, compatibility issues, slow installs are also an issue, but I think they are secondary.