Who cares if you're 10x, we'll all be 10x dead at some point. In 50-100 years I doubt most of your 10x work will still be around. Might as well go enjoy some life before it ends.
2) The premise of the 10xers not being around in 50-100 years could be correct. It depends on the amount of money invested in anti-ageing technology.
Coming down on one side or another, in a binary fashion: I think your comment is false.
> Until better than marginal gains are realized, I would say it's premature to hold massive lifespan lengthening out as a realistic possibility since we don't know what road blocks lie ahead. Sure, it's possible in the 'anything is possible' sense, but, IMO, not as a practical consideration.
People are working on the problem of radical live extension today. So even if you consider it impractical, that's certainly not a view held by everyone.
Plus, a gradual improvement is all that's needed. As long as someone can live long enough to reach longevity escape velocity[1], that's the problem solved!
[0] http://www.kurzweilai.net/fullerene-c60-administration-doubl...