Don't you have to intercept/reject TLS to make that workable? Otherwise the user (or malware) can upload or download anything and all you see at the network level is a destination IP address. If a user has admin rights (which is common in corporate environments) then they can install software which can mimic a browser using HTTPS.
At the network level it is difficult to identify what program generated a request and which user was running that program. I am very sceptical of the heuristic approaches that try and solve this problem (Palo Alto App-ID for example) that display quite shocking emergent properties.
Surely it is technically preferable to track network requests within the OS and browser where you can actually get at information reliably without any hocus pocus. If a user can avoid it by just "shutting it down" then they can also remove the AV, connect to a proxy and spend the afternoon uploading client lists to a porn site.