Coming from the compiler side of things, you're sacrificing in usability to make it possible for the JIT compiler to optimize the code further. If you allocate all memory ahead-of-time, the GC never needs to operate on that region, which gives you substantial performance improvements.

This is definitely a trade-off, but it's my understanding that asm.js makes more sense as a target for compilers to emit code for, rather than for hand-writing. Would you hand write an entire application in x86 assembly? Probably not...