I know, I know, having been cured of cancer probably influences my opinion just a bit, but I think Houston's a pretty damned cool town :-)
I think every place has it's own charms, you just have to look for it - in some places you have to look harder than others, sure. I hated NYC the first year I lived there, and later came to really like it. But, I'm the kind of person who'd enjoy living in the Mojave just as much as I'd enjoy living in Manhattan - it's all good, and every day I'm breathing is a great day to appreciate wherever the hell I happen to be.