This is something I've wondered about ever since reading "Life's Ratchet" - if it was possible back then for a molecule to be self-replicating, then it seems like it should still be possible today (maybe with a different molecule), and therefore it seems possible or even likely that it's already happening all the time all around us. It's fun to think about seeds for new evolutionary paths being generated constantly at a scale so tiny we can barely perceive them. Maybe we will start finding instances of replicator molecules in all sorts of places once we know what to look for. If we master the chemistry to the point where we could design replicators for other places, we might even be able to kick off life in the nicer neighborhoods of our solar system.