Generally, yes, driving will always beat a bus. Train is always the way to go, as there is no traffic on the tracks (a majority of the time).
To me, it's a common misconception that driving is quicker. In Chicago, driving is almost never quicker (due to traffic), and regardless, it's always wasted time. You can't DO anything while you're driving. Taking the bus or the L, at least you can work on what you need to work on.