This happens in business class on many airlines (long haul). I've never felt it to be a problem at all.

Seating that's displaced far from the centerline of the aircraft would also be less comfortable during banked turns. The sensation of falling or rising would be greater the farther you are from the centerline because you're moving through a larger displacement around the axis, and also at a higher rate.

Incidentally this style of aircraft looks really wide and flat.

This, if you've ever ridden in the jump seats of a jet and felt your head and guts go sideways during climb out it is very disconcerting. You know that feeling that the jet it tilting way up when your sitting forward? You get the tilt is really sideways when you are sitting sideways. I expect you get used to it but it no doubt makes those seats hard to sell.