I've seen a huge number of sites over the years stop working because they redesign to incorporate javascript; yet, when I visit them at work (with a javascript-enabled browser) their shiny new site doesn't actually have any new features.
Things that don't need javascript:
--Form verification (you should always be doing this on the server, and optionally in client-side javascript)
--<video> tag
--Popup site menus
--Web-based chat
--Webmail
--Message board comments (unless you locked yourself into Disqus)
--Nearly everything