Oh god no, Firewire is a particularly bad example of a keyed port.

When implemented cheaply using a split flanged socket, the plug can easily be pushed in backwards, spreading the flanges. Apple learned pretty quickly what a terrible idea that was, and switched to a design where there's a hard ABS ring inset in the aluminum exterior case. Unfortunately every other manufacturer continued with the shitty design.

On top of that, the power supply is 12v/1A, and is carried on one of the outside pins! If you shove it in backwards, power gets connected to data and fries the board. They should have used the central pins for power and ground.

I've personally seen at least a dozen cases of fried Firewire ports, including several epidemics where someone would fry ports on several computers using one bad device.