An airplane is a vehicle that wants to fly, a helicopter wants to crash. A helicopter is inherently unstable and requires constant adjustment. It has multiple single points of failure, any one of which will result inevitably in a crash. This is dealt with by insanely expensive quality control, constant inspections, and constant maintenance.
The quadcopter doesn't improve on this, it makes it worse. It has 4 engines - if one engine fails, it crashes. It has inherently 1/4 of the reliability of a single engine helicopter. Losing one rotor blade will also cause a crash, so its 1/4 of the reliability there as well. QA, maintenance, and overhauls will cost 4x as much.