It is worth looking at. There are multiple ways to connect events (signals/slots), and they encourage "Bind" these days, but you can still do Connect/Disconnect or use macro-based event maps (very MFC style).

But in general it's pretty good. There was a GSOC project this year to implement a DirectX backend to the Windows drawing system instead of GDI but I don't know how well that has got on. They overhauled the drawing system to using native drawing contexts on whichever platform you're running, so you can do aliasing etc.

It's worth a look I think, as it is quite easy to write something usable in it very quickly. There is no database support anymore though - wxODBC died a death.