Installing / on ZFS is fairly easy on most major Linux distributions, but Debian has been the main exception due to its initramfs generator lacking ZFS support. I am cautiously optimistic that will change.

If not, then this issue should go away when I publish ZFS support patches for syslinux later this year. syslinux is capable of generating initramfs archives on the fly, so adding ZFS support to it should largely eliminate the need for distribution-specific initramfs generators.