Yes, in Ontario Canada. It's home of BlackBerry (the smartphones company) and a hotbed for startups. Google has an office downtown in downtown Waterloo.
It is in downtown Kitchener; the city beside Waterloo. (That doesn't change the semantics, here.)
(Waterloo's downtown is branded "uptown". Urg.)
Or a district in Liverpool, a train station in London or a song by Abba.