Either you missed out on the last couple of months news coverage somehow or you are deliberately being obtuse in order to score 'points'. Not sure which.
Anyway, these days when people are talking about the Eastern Ukraine in terms of an area that you should not be flying planes over they are not quibbling over facts of geography but in relation to the ongoing attempt at secession in the Eastern part of the Ukraine. If you wish to have it specified by google map coordinates, lists of cities, an animated map of the moving frontier then I could probably comply with the demand but it isn't worth the trouble.
Currently 'don't fly your civilian aircraft over Eastern Ukraine' is something that you could take either as person informed about current events or as a cartographer.
By your standards we don't have a 'middle America', there is no 'eastern Cyprus' and so on.
It's contested territory at best right now, quite possibly at some point in the future it won't be called Ukraine at all.