Only special ref objects are mutable in Clojure (via STM). I was talking of `setq` in the context of mutating normal variables. It's perhaps a bad idea, and I have to study how LT manages its plugin system without mutation.
(deftype SomeTypeWithMutableFields [^:unsynchronized-mutable some-mutable-field ^:volatile-mutable another-mutable-field])
:unsynchronized-mutable corresponds to a normal mutable Java variable, and :volatile-mutable corresponds to a Java variable with the volatile modifier.
They are private by default, you can only set! them within the lexical scope of the deftype definition. If you needed to expose fast host mutation to the public, I would create a setter/getter interface (via definterface) and implement it on your deftype and use set! locally to mutate the field there.