In particular, an attacker having access to the ciphertext at two or more different times violates EncFS's security assumptions; undetected malicious modification of files is also feasible in this scenario.
Many encrypted filesystems do not include such a property in their design criteria - for example, XTS mode as-is is not suitable for use in this scenario either, so please also try to avoid putting TrueCrypt (et al) on Dropbox!
For a broad general example of what a system would look like which tries to address this use case more naturally and effectively (although, caveat: I have not reviewed it in great detail myself), please see Tahoe-LAFS.