In fact, you could argue that Uber doesn't give them directions and that they drove down the wrong street of their own volition. More to the point: this thinking is just a distraction.
To further elaborate on that point, I meant that driving is a fairly risky activity that we engage in. A driver is accepting that risk in order to make a living. A client is obviously not responsible if an accident happens, as the driver has accepted the risk associated with the transaction, in exchange for money.
However, for every extra minute or mile on the road, a driver has a slightly higher chance of getting into an accident. Uber has made thousands of such calls, for absolutely no good reason and with no monetary benefit for the drivers. Although not directly responsible for possible accidents, the sheer number could have conceivably contributed to increasing the odds of one such accident/injury or even death (in a worse case scenario) happening. Which makes Uber's actions even shittier in my books.
I understand that most people here don't see it that way.
Note: Of course my assumption about the odds might be entirely false, if I misunderstood the way Uber works. For example if cars are just running around town until a fare is requested, instead of being parked somewhere.