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The prescription API is for existing (Walgreen's) prescriptions or transferring a Rx, it doesn't allow you to submit a new Rx, just order refills, etc.

I believe AllScripts' E-Prescribe pretty much has the market cornered for non-hospital pharmacies. I would think most hospital EMRs would have an integrated eprescribe for their internal pharmacy orders.

I was part of an AllScripts deployment in a previous job. It is truly awful, as are their deployment teams that you work with. They actually recommended we put the web, database, app, and other tiers on a single subnet/VLAN. "We can't help you do it any other way, we've not done that."

I think you mean Surescripts, rather than AllScripts (EMR vendor).

EMRs have this data and some of them expose it via APIs but there's usually more of an approval process than imagine Walgreen's requires.

http://surescripts.com - they pretty much own the market