I run the Ghostery extension and a year or so ago I noticed that when visiting YouTube ~15 analytic trackers were being blocked. Turns out a couple of extensions were injecting tens of trackers into popular sites (without my express permission), and I would have had no idea unless I had another extension to block and report this activity.
My girlfriends computer is worse - her extensions seem to inject actual adverts into lots of her pages. I asked her why there was an obnoxious "click the bottle to win 1000000$" flash advert on Facebook and she thought it was just how Facebook is. Same thing for YouTube and other popular sites.