+this.
Another way of putting it: A well-designed structure should minimize random, unintentional air exchange, but provide sufficient deliberately-engineered ventilation to keep the air and people happy. For efficiency, that ventilation should go through a heat recovery ventilator (HRV) or energy recovery ventilator (ERV) as appropriate to the climate and budget. (An energy recovery ventilator also exchanges moisture).
Beyond Chlupp, Lstiburek is a great engineer and writer on these topics.