How am I supposed to spend time with my family if I'm expected to be at work from 9am until 7pm (that would be a 50 hour work week)? Also, I assume that most startups either offer unlimited vacation (which from what I've heard means you don't get to take a lot of vacation), or they offer 2 weeks of vacation to start out. So, I have a couple hours at home with my family and only a couple weeks out of the year to take time off to spend with them. That doesn't add up.
Maybe I'm incorrect about the average startup, but at least from what I've seen and been offered, I would have to give up too much of my family time to work for one.