Nowhere beside Downtown, and maybe one other neighborhood, is worth living in right now, and the rent in those areas are starting to sky rocket.
Living in Cleveland I sometimes get contact by companies in Detroit looking for developers. I recently considered taking a position, but the housing situation made me reconsider.
It was either pay 3X the rent for an apartment Downtown, compared to my apartment in Cleveland, or have a 45-60 commute every day. Even with the increase in salary it wasn't worth the move.