It's a good sign that there are no comments yet (less than 44 minutes after posted).
I've seen the video version before, but it never fails to inspire me, so I think I'll go watch it now as well.
Really gets you to think in terms of the impact you could have and what intentional steps you could take to get there.
Maybe even reading less Hacker News. I can't think of a more appropriate place for this message. As the monthly Who's Hiring posts are effectively automatic, I suggest this talk should appear regularly as well.
Transcript of the original version of this talk: http://www.paulgraham.com/hamming.html