Something many folks fail to realize is that the War on Drugs has origins dating back a century ago: [1]

    Although Nixon declared the War on Drugs public enemy number one in
    1971,[14] the policies that his administration implemented as part of the
    Comprehensive Drug Abuse Prevention and Control Act of 1970 were a
    continuation of drug prohibition policies in the U.S., which started in
    1914

During this time there have been many wars fought where a principle component of the reason for the war was the War on Drugs.

In Mexico, the "official count" (always an underestimate) is now over 100k. [2]

In Afghanistan, Opium has played a major role in almost every war and genocide, where deaths have exceeded several million. [3][4][5]

You can do your own research for the number of deaths that the War on Drugs has caused in just about every country on the planet (Russia, China, all countries in South America, especially Columbia). Summed up "millions of deaths" is easily accounted for by bad drug-related policies.

And that's not even counting all the drug-related deaths that are caused thanks to illicit drugs being illicit. How many people have blamed the deaths of their loved ones on "illegal drugs" when the truth is that it is the War on Drugs that killed their son, spouse, loved one? When you don't know what you're actually ingesting/smoking/injecting (as a consequence of the substances being illegal and not regulated), again the death toll leads to the millions.

And then there's the number of lives ruined (not killed)...

    [1] https://en.wikipedia.org/wiki/War_on_Drugs#History
    [2] https://en.wikipedia.org/wiki/Mexican_Drug_War
    [3] https://sites.google.com/site/afghanholocaustafghangenocide/
    [4] http://www.countercurrents.org/polya270611.htm
    [5] http://www.tomdispatch.com/post/175225