The valuation number is misleading. You're looking at the snapshot price of a relative small fraction of Airbnb's equity at a particular moment in time; just as 1,000,000 shares of XYZ will likely trade at a lower price than 1 share, so too might the valuation be lower for the whole company.
More importantly, these aren't common shares; they're shares with privileges attached to them, and thus command a higher value.
Finally, VC's perspective towards share valuation is different than that of a "value investor"; a VC looks at the shares as if they were options, with a limited (1x investment) downside but an uncapped upside.
These aren't my insights; they're taken from a bulleted list Andreesen twerped last night. They sound convincing to me.