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Workflowy has keyboard shortcuts for pretty much everything. I've been using it for about 6 months now and I swear by it.

Workflowy is an enlighteningly simple app (it's really just bullet lists with zooming) but it's incredibly effective for what it does, and the free-form nature of it makes it easy to just brain-dump random notes to get your thoughts out into text. I use it to do rubber ducking [1], because just the act of putting my problem into text helps me organize my thoughts. I can't say enough good things about it.

[1] http://c2.com/cgi/wiki?RubberDucking

Not sure about plugins, but adding keyboard shortcuts shouldn't be hard, via a browser extension for example.

I use workflowy everyday and it's really cool; it doesn't feel very actively developed though, and that's a shame.

Also, try their search and hashtags: just brilliant!

you don't need a mouse, everything has keyboard shortcuts. hit ctrl-? for a list.