Just to nitpick a bit, voter turnout was nowhere near 100% in 2008, so no, we can't say that 52% of Californians were toxic in 2008 (not counting LA obviously). The types of donations that went into the pro Prop 8 campaign helped fuel a marketing effort intended to stir up emotions among the anti-gay crowd. That was pretty toxic.

The idea of explicitly enshrining our collective dislike of gay people is also just pretty toxic all by itself, naturally, but that's a slightly different tack.