Colin, congrats on the success! It's nice to hear an App Store success story instead of the usual bad news.
For us, the only issue is communication- we've now had a Kindle companion application, Kindling, in review for 94 days, without any communication outside of form responses from Apple.
We take the long view- the App Store is currently the best mobile platform, but we're working on expanding our business to other platforms. I think it's pretty crazy for any developer to be focused on one platform exclusively, and have 100% of their revenue capable of being destroyed with a single click of the 'Remove from Sale' button in Cupertino.