If you're operating on a massive enterprise scale, it's probably not going to be good enough for your hardware. The HipHop VM might be a saving grace if you're already built on PHP, but pragmatically it's probably a better idea to choose a more matured solution (probably something on the JVM).
If you're doing something that is algorithmically intensive (video encoding as an arbitrary example) PHP is going to be a bad fit.
However, if you, like the vast majority of developers, are working on a website that's main technical purpose is to store data of some sort to a back end and retrieve it later for display and you're not yet operating on a large scale (1M+ users) then PHP itself is probably not going to be your bottleneck for a long time.
If you're a fan of benchmarking, techempower does a good job of unbiased comparisons (although keep in mind these are just benchmarks. It doesn't account for how a particular language or framework is optimized for): http://www.techempower.com/benchmarks/