He also names Schmidt & Zuckerberg as heavy players that are trying to 'fight' internet.
Google, with its resources and the data they have about all of us, certainly has the best position today to try to control/conquer the internet (as MS was in 1995). Dave is sure they'll fail (I hope he is right)
He goes on to make a comparison to Twitter, and how they are concerned that if they make the service too open, then developers might create something that competes with the service or renders it obsolete. And he's saying that reluctance to embrace the openness of the internet will result in failure in the same manner that it did for Microsoft.
(not that I agree with this piece; this is just my interpretation)
So he thinks that no one can really has control over anything once the Pandora's box has been opened.
Or, actually, he's saying that no one can beat nature. Because, you know, it just goes on and on.