I've tried, but:
* Typing speed turned out to rarely be a meaningful limit on my productivity with coding, writing, or general tasks.
* Using a nonstandard layout for my home desktop meant reconfiguring several laptops as well, then still having trouble any time I use any other computer.
Typing speed IS beneficial up to a point, but touch typing on QWERTY is already going to be near or past the point of diminishing returns for many users. It was fun to play with, but not worthwhile to do long-term. (YMMV)