Assuming this simulation is largely parallelizable (likely, because matter acts locally), then for whatever the hardware it ran on cost, in 15 years it should take 5 * 60/1000= .3 seconds per frame (not 0.04s, for 25 fps). In 20 years, it would be .03s (33 fps). But consider that fakey shortcuts that look OK will be assiduously sought.
Moore's Law (and especially this corollary) have a few years left, but maybe not 15 years... However, I'm optimistic about another technology taking over (as has happened previously). There's plenty of scope, considering what brains and cellular machinery can do. (I think the quantum stuff is BS. Probably.)
I think you meant to say 5:20 ^^
There are also some really rough tessellation techniques in use to simulate ground snow walking in games out now, like that Assassins Creed with the native americans.
http://lesterbanks.com/2012/03/10-great-examples-of-naiad-in...
It depends on the accuracy of them and the resolution / speed they're going to get rendered at.