None of us will know if Mark Cuban is truly happy. And we cannot tell for sure if you will ever be happy. What is clear from all you have said, is that riches will not make you happy. You have studied and worked to get where you are. You do not live in isolation so there must be others who have benefited from you being you. I do not doubt your temptation to give up, but I hope you choose to improve. Losing someone who has made such an impact would surely be painful to those you touched.
Though you should not strive solely for wealth, you do not have to refuse that which comes to you. I believe, along the way you can find happiness.
Hang in there.