I use it exclusively for all my clojure work and have been for a while. It works well, and especially shines with its REPL integration, and when paired with Leiningen. Chris really has done a great job at keeping things minimal and elegant.

However, I use it because I'm a vim user and clojure has never had stellar support in vim (whereas Light Table--or rather CodeMirror's editor--has vim bindings). If you're an emacs user, Light Table might not offer anything over existing emacs tools.