It's a blessing, not an obligation or a demand or a condition of use.

Unlike the JSON license clause "The Software shall be used for Good, not Evil", the SQLite blessing doesn't put any restriction on your "freedom to run the program, for any purpose (freedom 0)" or on any of the other freedoms listed by the FSF.

It's no different from putting this in a library:

# This work is dedicated to the public domain.

# I hope you enjoy using it!

No one could argue that if you didn't enjoy using the library (maybe the API is a confusing mess) you would somehow be in violation of the license.

p.s. I upvoted your comment because I think you raised an interesting point!