Always hard to predict, but one area where I'm sure there's lots of room is starting startups in industries that didn't previously have them. To use one example of many, LendUp.
Many of the more successful startups recently follow the same pattern: they work to eliminate one job description. Zillow = real estate agents, Square = cashiers, LendUp = bankers, Yelp = food critics, AirBnB = hoteliers. Heck, the initial apps that made the personal computer successful also had that pattern: Visicalc = accountants, Adobe = print shops. Jobs and Gates got rich because they controlled the infrastructure that these businesses built upon, but the folks who built those apps also got fairly rich as well. Heck, Bill Gates's first programming job was writing a payroll program, and his first business venture was software for traffic counters.