The only thing that drives me crazy about the save/do-you-want-to-reload prompt is actually a git related issue. When you commit, git updates all committed files in some way that triggers vim change detection. You go back to vim, write some code, try to save and then you get this DANGER WILL ROBINSON message.
It's horrible because you're not quite sure sometimes if there was a legitimate change made in another process that you're now about to undo. Half the time I end up copying the lines I know I added, allowing a reload, and then pasting them back in, just to be safe.