I think there are a few benefits.

First and foremost, schemas are simple, minimal, easy to read and write, and gracefully extend Clojure's existing type hints. This means that (in my biased opinion) they are significantly better for documentation, which was the primary motivation for developing them.

Second, schemas are data, so it's easy to do more with them beyond documentation. Runtime data validation is one such use, but we can also easily do things like generate core.typed annotations, generate model classes for clients, generate test data, and so on.