I'm guessing that he's being a bit sarcastic since this would be an extremely hodgepodged setup, but I have thought about doing something like this for a home server/personal computer setup.

My thoughts where to have something like a rackmounted server machine in my basement with multiple storage drives, oodles of RAM, CPU, and a video card with it all running under an ESX (or whatever) install. Over the hypervisor I could then have running a headless NAS OS (e.g. UnRAID or FreeNAS) for my backups/media/etc and then a full-blown gaming PC running Windows with the GPU being virtually attached to it. Then (oh there's more) I could run all of my keyboard, video, mouse, and USB cables for the virtual gaming PC up through my house to where my desk is located. I figure that with this setup I could consolidate a several physical computers (gaming pc, NAS, etc) into one workhorse computer which would save space and possibly some electricity.