What's an example of something non-interactive that ed is good for that you can't easily do with other tools?
ed has a more concise syntax for joining arbitrary lines of a file (by line number or pattern) and then saving the file (by way of a temp file in $TMPDIR). You could do this with awk and perhaps with other standard tools (note: I don't consider perl to be "standard"). But I think it's safe to say the ed script would always be shorter. ed's syntax for deleting and moving arbitrary lines is similarly concise. For these specific tasks, it's not going to be easy to win at code golf using awk or other tools... and in some cases it may be impossible.
That said, I've recommended learning Python to a few people, but have never even suggested anybody learn sed or awk.