For the uvar example you could get could get close (from news.arc):

  (mac uvar (u k) `((profs* ,u) ',k))
  (def user-age (u) (hours-since (uvar u created)))

Without a macro you'd have to call uvar like: (uvar u 'k). For this example I'd favor 'k because it makes the behavior clearer.

(Did you mean uvar instead of upvar?)