We (SpiderOak) have been working on a framework called Crypton[1] for the last few months that allows you to create cryptographically secure web apps. We're trying to get the 0.2 release and new website[2] out this week.
I'm currently the only dev on the project and we could always use more eyeballs. I'm working through a code review right now to improve the existing features, but I'm also half way done implementing shared containers and realtime public key messaging. The idea is that you don't new to understand the crypto if you use the framework. We are in the process of getting a professional security audit.
[1] https://github.com/SpiderOak/crypton [2] https://crypton.io