Why not just leave the "{{ }}" out and assume the mammouth file is 100% PHP?
The way around php has it is both annoying, since most php is not mere template anymore, and error-prone, thanks to the potential problems from trailing whitespace.
You are supposed to leave out the closing ?> in the PHP file - then you don't have that problem.
Inverting doesn't really make any sense:
<P><?=$message?></P>
The HTML is primary, the PHP is used to output whatever is needed.As for your little snippet, inverting does make sense:
<?php
// ... 1000 lines of php
...?><p><?=$message?></p><?...
// ... 1000 lines of php
?>
But tacky little examples aside, there's nothing stopping <?= tags from working just as they always have once you've escaped into html.