IIR, DOTA was a mod for Warcraft III, and Valve hired the mod team on to build the sequel based on Source.
from WP "According to Valve's founder and managing director, Gabe Newell, the company's investment in Dota was sparked from the collective interest of several veteran employees, including Team Fortress designer Robin Walker, programmer Adrian Finol and project manager Erik Johnson, all of whom had attempted to partake in team play at a competitive level."
So it might be a popular game, but it's not a major development for Valve in the sense that Team Fortress, Portal 2 or HF2 was...and also demonstrates some of the internal culture issues Valve has.