Silicon Valley. I grew up dreaming about Livermore Labs, Xerox PARC, Hewlett Packard (in its day), Apple. Now everything is in the city, and each start up as vapid and pointless as the last.
Another problem is that there are not many properly educated people to establish and run labs like this thanks to our education system falling apart. But you won't hear anybody talking about that. Things will just get worse and worse.