Right now the most common antibiotics we have (eg penicillin + synthetic derivatives) use a B-lactam ring to disrupt cell wall production. Now we start to see bacteria that are resistant to this attack, eg MRSA (Methicillin-resistant staphylococcus aureus), that in worst-case scenarios make even simple surgical procedures life-threatening.
Then we bring in the big guns, things like Vancomycin that disrupt cell wall production using different methods. But then we start to see Vancomycin-resistant microorganisms. So governments limit Vancomycin use so as to not give bacteria the opportunity to evolve and develop resistance. Thus drug manufacturers are unwilling to research new antibiotics because they can't make a profit off of restricted-access antibiotics.
So it's largely a game of cat and mouse that could very well result in a deadly worldwide epidemic. New ways of looking at the problem such as the one described in the article could, without even being hyperbolic, save billions of lives.